NIH Clinical Center
Dept. of Lab Medicine | Dept. of Transfusion Medicine | Anatomic Pathology Test Guide > Lab Test
 Lab Test
 
 Test Description
Panel Name:
Test Name:
Toxicology Screen, Blood
Panel Tests:Acetaminophen, Acetylsalicylate, Advil®, Ambien®, Aminophylline, Amitriptyline, Amobarbital, Amytal®, Anafranil®, Ansaid®, Aspirin®, Ativan®, Bactrim®, Barbital, Benadryl®, Bupropion, Butabarbital, Butalbital, Butazolidin®, Butisol®, Cacao Bean Products, Caffeine, Calan®, Carbamazepine, Carbatrol®, Cardizem®, Carisoprodol, Celexa®, Celontin®, Chlordiazepoxide, Citalopram, Clinoril®, Clomipramine, Clozapine, Clozaril®, Codeine, Dalmane®, Darvon®, Depakene®, Desalkyl Flurazepam, Desipramine, Desyrel®, Diazepam, Dilantin®, Diltiazem, Diphenhydramine, Doriden®, Doxepin, Doxylamine, Effexor®, Elavil®, Ethchlorvynol, Ethosuximide, Felbamate, Felbatol®, Fenoprofen, Fiorinal®, Flagyl®, Fluoxetine, Flurazepam, Flurbiprofen, Gabapentin, Gantrisin®, Glutethimide, Ibuprofen, Imipramine, Indocin®, Indomethacin, Ketoprofen, Ketorolac, Ketorolac, Kutrase®, Lamictal®, Lamotrigine, Librium®, Lidocaine, Lorazepam, Ludiomil®, Maprotiline, Mebaral®, Mephobarbital, Meprobamate, Methsuximide, Methyprylon, Metoclopramide, Metronidazole, Midazolam, Miltown®, Mirtazapine, Motrin®, Mysoline®, Nalfon®, Naprosyn®, Naproxen, Nembutal®, Neurontin®, Nicotine, Noludar®, Nordiazepam, Norpramin®, Nortriptyline, Nuprin®, Orudis®, Oxazepam, Pamelor®, Paroxetine, Paxil®, Pentobarbital, Pentothal®, Pentoxyfilline, Phenobarbital, Phenylbutazone, Phenyltoloxamine, Phenytoin, Phosphenytoin®, Placidyl®, Primidone, Propoxyphene, Prozac®, Quinidex®, Quinidine, Reglan®, Remeran®, Restoril®, Salicylate, Secobarbital, Seconal®, Serax®, Sertraline, Sinequan®, Soma®, Sulfadiazine, Sulfamethoxazole, Sulfapyridine, Sulfisoxazole, Sulindac, Surmontil®, Tegretol®, Temazepam, Theobromine, Theophylline, Thiopental, Ticlid®, Ticlopidine, Tigan®, Tofranil®, Tolectin®, Tolmetin, Topamax®, Topiramate, Toradol®, Tramadol, Tranxene®, Trazodone, Trental®, Trimethobenzamide, Trimethoprim, Trimipramine, Tylenol®, Ultram®, Unisom®, Valium®, Valproic Acid, Venlafaxine, Verapamil, Versed®, Wellbutrin®, Xylocaine®, Zarontin®, Zoloft®, Zolpidem .
LIS Test Code:DSS1
Synonyms: Drug Screen, Stimulants, Sedatives, Psychotropics, Barbiturates, Anticonvulsants, Analgesics
Department:Laboratory Medicine
Lab Area:Mayo Medical Labs
Telephone:301-496-5972
TAT:2-6 days
 Specimen Collection
Source:

Site:

Container:Red (Plastic)

Micro. Container:


Collection Instructions:

Delivery Instructions:Send specimen to 2C324 or Tube Station 321
Specimen Type: Blood
Frequency / Restrictions:
 Expected Values/Results
Ranges and Interpretation:

Toxicology Screen, Blood
Performed at Mayo Medical Labs, Rochester MN
Effective 15Mar95 - present:
This test specifically screens for each of the drugs listed below. Results for drugs indicated by # are quantitative in blood, all others are qualitative.

Analgesics:

Acetaminophen (Tylenol®)#
Acetylsalicylate (Aspirin®)#
Advil® (Ibuprofen)
Ansaid® (Flurbiprofen)
Aspirin® (Acetylsalicylate)#
Butazolidin® (Phenylbutazone)
Clinoril® (Sulindac)
Darvon® (Propoxyphene)#
Fenoprofen (Nalfon®)
Flurbiprofen (Ansaid®)
Ibuprofen (Motrin®, Advil®, Nuprin®)
Indocin® (Indomethacin)
Indomethacin (Indocin®)
Ketoprofen (Orudis®)
Ketorolac (Toradol®)
Midazolam (Versed®)
Motrin® (Ibuprofen)
Nalfon® (Fenoprofen)
Naprosyn® (Naproxen)
Naproxen (Naprosyn®)
Nuprin® (Ibuprofen)
Orudis® (Ketoprofen)
Phenylbutazone (Butazolidin®)
Propoxyphene (Darvon®)#
Salicylate#
Sulindac (Clinoril®)
Toradol® (Ketorolac)
Tolectin® (Tolmetin)
Tolmetin (Tolectin®)
Tramadol (Ultram®)
Tylenol® (Acetaminophen)#
Ultram® (Tramadol)
Versed® (Midazolam)

Anticonvulsants:

Carbamazepine (Carbatrol®, Tegretol®)#
Carbatrol® (Carbamazepine)#
Celontin® (Methsuximide)#
Depakene® (Valproic Acid)#
Dilantin® (Phenytoin)#
Ethosuximide (Zarontin®)#
Felbamate (Felbatol®)#
Felbatol® (Felbamate)#
Gabapentin (Neurontin®)#
Lamictal® (Lamotrigine)#
Lamotrigine (Lamictal®)#
Mebaral® (Mephobarbital)#
Mephobarbital (Mebaral®)#
Methsuximide (Celontin®)#
Mysoline® (Primidone)#
Neurontin® (Gabapentin)#
Phenobarbital#
Phenytoin (Dilantin®, Phosphenytoin®)#
Phosphenytoin® (Phenytoin)#
Primidone (Mysoline®)#
Tegretol® (Carbamazepine)#
Topamax® (Topiramate)#
Topiramate (Topamax®)#
Valproic Acid (Depakene®)#
Zarontin® (Ethosuximide)#

Barbiturates:

Amobarbital (Amytal®)#
Amytal® (Amobarbital)#
Barbital
Butabarbital (Butisol®)#
Butalbital (Fiorinal®)#
Butisol® (Butabarbital)#
Fiorinal® (Butalbital)#
Mebaral® (Mephobarbital)#
Mephobarbital (Mebaral®)#
Mysoline® (Primidone)#
Nembutal® (Pentobarbital)#
Pentobarbital (Nembutal®)#
Pentothal® (Thiopental)#
Phenobarbital (many products)#
Primidone (Mysoline®)#
Secobarbital (Seconal®)#
Seconal® (Secobarbital)#
Thiopental (Pentothal®)#

Psychotropics:

Ambien® (Zolpidem)
Amitriptyline (Elavil®)#
Anafranil® (Clomipramine)#
Ativan® (Lorazepam)
Bupropion (Wellbutrin®)#
Celexa® (Citalopram)
Chlordiazepoxide (Librium®)#
Citalopram (Celexa®)
Clomipramine (Anafranil®)#
Clozapine (Clozaril®)
Clozaril® (Clozapine)
Cocaine*
Codeine*
Dalmane® (Flurazepam)
Desalkyl Flurazepam (metabolite)
Desipramine (Norpramin®)*#
Desyrel® (Trazodone)#
Diazepam (Valium®)#
Doxepin (Sinequan®)#
Effexor® (Venlafaxine)
Elavil® (Amitriptyline)#
Fluoxetine (Prozac®)#
Flurazepam (Dalmane®)#
Imipramine (Tofranil®)#
Librium® (Chlordiazepoxide)#
Lorazepam (Ativan®)
Ludiomil® (Maprotiline)*
Maprotiline (Ludiomil®)*
Mirtazapine (Remeran®)
Nordiazepam (Tranxene®)#
Norpramin® (Desipramine)*#
Nortriptyline (Pamelor®)*#
Oxazepam (Serax®)#
Pamelor® (Nortriptyline)*#
Paroxetine (Paxil™)*
Paxil™ (Paroxetine)*
Prozac® (Fluoxetine)#
Remeran® (Mirtazapine)
Restoril® (Temazepam)#
Serax® (Oxazepam)#
Sertraline (Zoloft®)#
Sinequan® (Doxepin)#
Surmontil® (Trimipramine)#
Temazepam (Restoril®)#
Tofranil® (Imipramine)#
Tranxene® (Nordiazepam)#
Trazodone (Desyrel®)#
Trimipramine (Surmontil®)#
Valium® (Diazepam)#
Venlafaxine (Effexor®)
Wellbutrin® (Bupropion)#
Zoloft® (Sertraline)#
Zolpidem (Ambien®)

Sedatives:
Benadryl® (Diphenhydramine)#
Carisoprodol (Soma®)#
Diphenhydramine (Benadryl®)#
Doriden® (Glutethimide)
Doxylamine (Unisom®)
Ethchlorvynol (Placidyl®)
Glutethimide (Doriden®)
Meprobamate (Miltown®, etc.)#
Methyprylon (Noludar®)
Miltown® (Meprobamate)#
Noludar® (Methyprylon)
Placidyl® (Ethchlorvynol)
Soma® (Carisoprodol)#
Unisom® (Doxylamine)

Stimulants:
Caffeine (reported only if >15 mcg/mL)
Nicotine*
Theobromine (Cacao Bean Products)
Theophylline (Aminophylline, etc.)#

Sympathomimetics:

None

Other:
Bactrim™ (Sulfamethoxazole,
Trimethoprim)
Calan® (Verapamil)
Cardizem® (Diltiazem)
Diltiazem (Cardizem®)
Flagyl® (Metronidazole)
Gantrisin® (Sulfisoxazole)
Kutrase® (Phenyltoloxamine)
Lidocaine (Xylocaine®)#
Metoclopramide (Reglan®)
Metronidazole (Flagyl®)
Pentoxyfilline (Trental®)
Phenyltoloxamine (Kutrase®)
Quinidex® (Quinidine)#
Quinidine (Quinidex®)#
Reglan® (Metoclopramide)
Sulfadiazine
Sulfamethoxazole (Bactrim™)
Sulfapyridine
Sulfisoxazole (Gantrisin®)
Ticlid® (Ticlopidine)
Ticlopidine (Ticlid®)
Tigan® (Trimethobenzamide)
Trental® (Pentoxyfilline)
Trimethobenzamide (Tigan®)
Trimethoprim (Bactrim™)
Verapamil (Calan®)
Xylocaine® (Lidocaine)#

Note: Digoxin and lithium are not detected in these procedures.
*Drug detectable only when present at toxic levels.
#Drug is quantified and reported with reference range.
Note: Drugs not quantified do not have established reference ranges.

Organisms Reported:
Alert Limits:

 Additional Test Information

Comments:

Choose a more selective drug screen if possible.
The Toxicology screen tests for a broad spectrum of drugs in serum.

Positive results are definitive. Quantitative results are reported with reference range, when clinically relevant for serum. This test is designed to detect drugs that have toxic effects where clinicians can initiate treatment to counteract those effects. The test is intended for use by a physician to manage an apparent overdose, intoxicated patient, or to determine if a specific set of symptoms might be due to the presence of a drug. The test was not designed to screen for intermittent use of illicit drugs. For intermittent drug use, serum blood levels of most illicit drugs would be below the detection threshold for this test. The Toxicology Screen on blood specifically screen for each of the drugs listed on the  chart.

Drugs of toxic significance that are not detected by this test are: digoxin, lithium, and marijuana.

This test specifically screens for each of the drugs listed below. Results for drugs indicated by # are quantitative in blood, all others are qualitative.

Analgesics:

Acetaminophen (Tylenol®)#, Acetylsalicylate (Aspirin®)#, Advil® (Ibuprofen), Ansaid® (Flurbiprofen), Aspirin® (Acetylsalicylate)#, Butazolidin® (Phenylbutazone), Clinoril® (Sulindac), Darvon® (Propoxyphene)#, Fenoprofen (Nalfon®), Flurbiprofen  Ansaid®), Ibuprofen (Motrin®, Advil®, Nuprin®), Indocin® (Indomethacin), Indomethacin (Indocin®), Ketoprofen (Orudis®), Ketorolac (Toradol®), Midazolam  Versed®), Motrin® (Ibuprofen), Nalfon® (Fenoprofen), Naprosyn® (Naproxen), Naproxen (Naprosyn®), Nuprin® (Ibuprofen), Orudis® (Ketoprofen), Phenylbutazone  Butazolidin®), Propoxyphene (Darvon®#, Salicylate#, Sulindac (Clinoril®),  Toradol®  Ketorolac), Tolectin® (Tolmetin), Tolmetin (Tolectin®), Tramadol (Ultram®), Tylenol®  Acetaminophen)#, Ultram® (Tramadol), Versed® (Midazolam).

Anticonvulsants:

Carbamazepine (Carbatrol®, Tegretol®)#, Carbatrol® (Carbamazepine)#, Celontin® Methsuximide)#, Depakene® (Valproic Acid)#, Dilantin® (Phenytoin)#, Ethosuximide (Zarontin®)#, Felbamate (Felbatol®)#, Felbatol® (Felbamate)#, Gabapentin (Neurontin®)#, Lamictal® (Lamotrigine)#, Lamotrigine (Lamictal®)#, Mebaral® (Mephobarbital)#, Mephobarbital (Mebaral®)#, Methsuximide (Celontin®)#, Mysoline® (Primidone)#, Neurontin® (Gabapentin)#, Phenobarbital#, Phenytoin (Dilantin®, Phosphenytoin®)#, Phosphenytoin® (Phenytoin)#, Primidone (Mysoline®)#, Tegretol®  (Carbamazepine)#, Topamax® (Topiramate)#, Topiramate (Topamax®)#, Valproic Acid  (Depakene®)#, Zarontin® (Ethosuximide)#.

Barbiturates:

Amobarbital (Amytal®)#, Amytal® (Amobarbital)#, Barbital, Butabarbital (Butisol®)#,  Butalbital (Fiorinal®)#, Butisol® (Butabarbital)#, Fiorinal® (Butalbital)#, Mebaral®  (Mephobarbital)#, Mephobarbital (Mebaral®)#, Mysoline® (Primidone)#, Nembutal®  (Pentobarbital)#, Pentobarbital (Nembutal®)#, Pentothal® (Thiopental)#, Phenobarbital  (many products)#, Primidone (Mysoline®)#, Secobarbital (Seconal®)#, Seconal® (Secobarbital)#, Thiopental (Pentothal®)#.

Psychotropics:

Ambien® (Zolpidem), Amitriptyline (Elavil®)#, Anafranil® (Clomipramine)#, Ativan® (Lorazepam), Bupropion (Wellbutrin®)#, Celexa® (Citalopram), Chlordiazepoxide (Librium®)#, Citalopram (Celexa®), Clomipramine (Anafranil®)#, Clozapine (Clozaril®), Clozaril® (Clozapine), Cocaine*, Codeine*, Dalmane® (Flurazepam), Desalkyl Flurazepam (metabolite), Desipramine (Norpramin®)*#,  Desyrel®(Trazodone)#, Diazepam (Valium®)#, Doxepin (Sinequan®)#, Effexor® (Venlafaxine), Elavil® (Amitriptyline)#, Fluoxetine (Prozac®)#, Flurazepam (Dalmane®)#, Imipramine (Tofranil®)#, Librium® (Chlordiazepoxide)#, Lorazepam (Ativan®), Ludiomil® (Maprotiline)*, Maprotiline (Ludiomil®)*, Mirtazapine Remeran®), Nordiazepam (Tranxene®)#, Norpramin® (Desipramine)*#, Nortriptyline (Pamelor®)*#, Oxazepam (Serax®)#, Pamelor® (Nortriptyline)*#, Paroxetine (Paxil™)*, Paxil™ (Paroxetine)*, Prozac® (Fluoxetine)#, Remeran® (Mirtazapine), Restoril® (Temazepam)#, Serax® (Oxazepam)#, Sertraline (Zoloft®)#, Sinequan® (Doxepin)#, Surmontil® (Trimipramine)#, Temazepam (Restoril®)#, Tofranil® (Imipramine)#, Tranxene® (Nordiazepam)#, Trazodone (Desyrel®)#, Trimipramine (Surmontil®)#, Valium® (Diazepam)#, Venlafaxine (Effexor®), Wellbutrin® (Bupropion)#, Zoloft® (Sertraline)#, Zolpidem (Ambien®).

Sedatives:
Benadryl® (Diphenhydramine)#, Carisoprodol (Soma®)#, Diphenhydramine (Benadryl®)#, Doriden® (Glutethimide), Doxylamine (Unisom®), Ethchlorvynol (Placidyl®), Glutethimide (Doriden®), Meprobamate (Miltown®, etc.)#, Methyprylon (Noludar®), Miltown® (Meprobamate)#, Noludar® (Methyprylon), Placidyl® (Ethchlorvynol), Soma® (Carisoprodol)#, Unisom® (Doxylamine).

Stimulants:

Caffeine (reported only if >15 mcg/mL), Nicotine*, Theobromine (Cacao Bean Products), Theophylline (Aminophylline, etc.)#.

Sympathomimetics:

None

Other:

Bactrim™ (Sulfamethoxazole, Trimethoprim), Calan® (Verapamil), Cardizem® (Diltiazem), Diltiazem (Cardizem®), Flagyl® (Metronidazole), Gantrisin®  (Sulfisoxazole), Kutrase® (Phenyltoloxamine), Lidocaine (Xylocaine®)#,
Metoclopramide (Reglan®), Metronidazole (Flagyl®), Pentoxyfilline (Trental®),
Phenyltoloxamine (Kutrase®), Quinidex® (Quinidine)#, Quinidine (Quinidex®)#,
Reglan® (Metoclopramide), Sulfadiazine, Sulfamethoxazole (Bactrim™), Sulfapyridine,
Sulfisoxazole (Gantrisin®), Ticlid® (Ticlopidine), Ticlopidine (Ticlid®), Tigan® (Trimethobenzamide), Trental® (Pentoxyfilline), Trimethobenzamide (Tigan®),
Trimethoprim (Bactrim™), Verapamil (Calan®), Xylocaine® (Lidocaine)#.

Note: Digoxin and lithium are not detected in these procedures.


*Drug detectable only when present at toxic levels.
#Drug is quantified in serum and reported with reference range.
Note: Drugs not quantified do not have established reference ranges.

Drugs in alphabetical order:
Acetaminophen, Acetylsalicylate, Advil®, Ambien®, Aminophylline, Amitriptyline, Amobarbital, Amytal®, Anafranil®, Ansaid®, Aspirin®, Ativan®, Bactrim™, Barbital, Benadryl®, Bupropion, Butabarbital, Butalbital, Butazolidin®, Butisol®, Cacao Bean Products, Caffeine, Calan®, Carbamazepine, Carbatrol®, Cardizem®, Carisoprodol, Celexa®, Celontin®, Chlordiazepoxide, Citalopram, Clinoril®, Clomipramine, Clozapine, Clozaril®, Codeine, Dalmane®, Darvon®, Depakene®, Desalkyl Flurazepam, Desipramine, Desyrel®, Diazepam, Dilantin®, Diltiazem, Diphenhydramine, Doriden®, Doxepin, Doxylamine, Effexor®, Elavil®, Ethchlorvynol, Ethosuximide, Felbamate, Felbatol®, Fenoprofen, Fiorinal®, Flagyl®, Fluoxetine, Flurazepam, Flurbiprofen, Gabapentin, Gantrisin®, Glutethimide, Ibuprofen, Imipramine, Indocin®, Indomethacin, Ketoprofen, Ketorolac, Ketorolac, Kutrase®, Lamictal®, Lamotrigine, Librium®, Lidocaine, Lorazepam, Ludiomil®, Maprotiline, Mebaral®, Mephobarbital, Meprobamate, Methsuximide, Methyprylon, Metoclopramide, Metronidazole, Midazolam, Miltown®, Mirtazapine, Motrin®, Mysoline®, Nalfon®, Naprosyn®, Naproxen, Nembutal®, Neurontin®, Nicotine, Noludar®, Nordiazepam, Norpramin®, Nortriptyline, Nuprin®, Orudis®, Oxazepam, Pamelor®, Paroxetine, Paxil™, Pentobarbital, Pentothal®, Pentoxyfilline, Phenobarbital, Phenylbutazone, Phenyltoloxamine, Phenytoin, Phosphenytoin®, Placidyl®, Primidone, Propoxyphene, Prozac®, Quinidex®, Quinidine, Reglan®, Remeran®, Restoril®, Salicylate, Secobarbital, Seconal®, Serax®, Sertraline, Sinequan®, Soma®, Sulfadiazine, Sulfamethoxazole, Sulfapyridine, Sulfisoxazole, Sulindac, Surmontil®, Tegretol®, Temazepam, Theobromine, Theophylline, Thiopental, Ticlid®, Ticlopidine, Tigan®, Tofranil®, Tolectin®, Tolmetin, Topamax®, Topiramate, Toradol®, Tramadol, Tranxene®, Trazodone, Trental®, Trimethobenzamide, Trimethoprim, Trimipramine, Tylenol®, Ultram®, Unisom®, Valium®, Valproic Acid, Venlafaxine, Verapamil, Versed®, Wellbutrin®, Xylocaine®, Zarontin®, Zoloft®, Zolpidem .


Methodology:


Cautions:

 
Archived Ranges:Historical Reference Ranges



 
 

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